Wearable Coagulation Monitor · DVT Detection

arteria

Proprietary biosensing meets on-device machine learning. Detecting DVT hours before conventional diagnostics can.

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A silent threat demands a
smarter response

Current DVT monitoring is fundamentally episodic — ultrasound at fixed intervals, D-dimer from venous blood draws. The diagnostic window is too narrow. By the time a clot is ultrasound-visible, the coagulation cascade has been active for hours. Clinical scoring systems (Wells, YEARS) and CT scans are fraught with delayed diagnosis and radiation exposure.

900K+
People affected by embolism annually
100K
Deaths per year in the US
66%
Of cases not diagnosed effectively
Real-Time Impedance Monitoring

"Arteria provides the first continuous molecular-level window into coagulation activation, detecting coagulation activation hours before any mechanical clot is ultrasound-visible."

Our Innovation

The Arteria System

Three integrated innovations in one wearable patch. Molecular-level coagulation monitoring that detects DVT hours before mechanical ultrasound, targeting the primary anatomical site of DVT initiation.

Proprietary Sensing
Architecture

Nanophotonic Biosensor

A novel biosensing approach optimized for coagulation biomarker detection at diagnostically relevant concentrations — achieving sensitivity levels unreachable by conventional electrode designs.

  • Multi-biomarker simultaneous detection
  • Sub-nanomolar sensitivity
  • Continuous electrochemical readout
Painless ISF Access

Minimally-Invasive Sampling

A microneedle array penetrates only the outermost skin layer, accessing interstitial fluid without blood contact. Biomarker concentrations in ISF closely track plasma levels — enabling continuous monitoring without any needle stick.

  • No blood draw required
  • Passive fluid sampling
  • Worn over target anatomical site
Real-Time Edge Inference

Temporal ML Classifier

A temporal machine learning model runs entirely on-device, learning the characteristic multi-biomarker trajectory of early coagulation cascade activation — issuing alerts hours before a clot becomes mechanically detectable.

  • 4-class risk output
  • On-device inference, no cloud
  • Wireless clinician dashboard

Engineering a molecular early warning system

A proprietary multi-biomarker panel. On-device temporal intelligence. Real-time cascade detection — issuing alerts hours before conventional diagnostics.

Biomarker A

Earliest Indicator

Released at the first moment of cascade activation. Most stable marker in interstitial fluid.

Biomarker B

Secondary Confirmation

Follows primary activation. Confirms coagulation cascade progression rather than transient fluctuation.

Biomarker C

Tertiary Signal

Elevated after clot consolidation. Provides systemic confirmation and rules out false positives.

From lab bench to standard
of care

Current
Stage 1

Prototype Development

Building our first-generation wearable architecture. Biosensor design, device fabrication, and processing pipeline are actively advancing toward clinical validation.

Stage 2

Bench Validation

In-vitro testing of biosensor performance, biomarker selectivity, and temporal ML model accuracy across synthetic plasma and ISF samples.

Stage 3
Stage 3

Clinical Pilot

Partnering with leading hospitals to monitor high-risk post-operative patients, validating detection lead-time over conventional imaging under real clinical conditions.

Stage 4
Stage 4

Regulatory Pathway

FDA De Novo submission with supporting clinical evidence. Pursuing breakthrough device designation to accelerate review timeline and access to market.

Stage 5
Stage 5

Commercial Launch

Scaling manufacturing, establishing hospital partnerships, and launching a continuous monitoring subscription model targeting high-acuity inpatient settings.

Who We Serve

Protecting those most vulnerable

Post-Operative Patients

Surgical immobility is the leading trigger of DVT. Arteria provides continuous watch during the highest-risk recovery window.

Cancer Patients

Procoagulant factors in oncology dramatically elevate clot risk. Arteria enables clinicians to preempt thrombotic events before they escalate.

Bedridden Patients

Long-term immobility patients in the ICU or care facilities represent a high-risk population with limited continuous monitoring options today.

Pregnant Women

Pregnancy increases DVT risk up to 5×. Arteria offers a non-invasive route to continuous surveillance without radiation or repeated blood draws.

Insurers & Healthcare Providers Arteria's early intervention model reduces downstream costs of missed clots — aligning clinical outcomes with payer incentives and value-based care frameworks.

Let's build the future of vascular health

Whether you're a healthcare provider, investor, or potential partner, we'd love to hear from you. Join us in revolutionizing clot detection.

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